I've changed meds at least twice. I'm not sure what I was on at first but after a year or two the RS decided to change it. At the time only one eye was wet. Maybe 3 years into the second med, the other eye turned wet. He did not tell me the name of the new med and I don't remember another change being mentioned and when I asked about it 3-4 years ago, I was on Eylea. I had pretty much stabilized at 5 week intervals between injections. A little over a year ago the RS told me a new drug was available and the results being reported were quite good. So he started me on Vabysmo. Unfortunately, my results were not as good as some report but it did extend me out to 8 weeks between injections, which I take as a win, especially since I have to travel 90-115 miles to have treatment.