I was diagnosed 13 years ago, my specialist insisted I take AREDS2 I have taken it every day, I don't know if it has kept it at bay, but I haven't had a shot for 5 years. I won't stop taking it just because it makes me feel like I am helping my eyes and one is even showing improvement. I haven't made any other changes in my life experience, so do they work? I don't know, but I feel better taking them.